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This is an extremely vague question. Perhaps it would help if you familiarized yourself with Visualforce first. Find some documentation and start reading up. Once you do that, have a look into this document on using the standard controller and extensions, which provides methods you can call around the save functionality. https://www.salesforce.com/us/developer/docs/pages/Content/apex_pages_standardcontroller.htm
If you are looking to avoid native VF tags that utilize view states and all that - just going HTML, read up on Javascript Remoting and Javascript Remote Objects.