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If you want to prevent all updates, you can disable this field for one or more profiles using field level security.
Please check out the following sections in the Salesforce Help:
Field access:
http://help.salesforce.com/apex/HTViewHelpDoc?id=customize_fieldaccess.htm&language=en
Page Layouts and Field Level Security:
https://help.salesforce.com/apex/HTViewHelpDoc/HTViewHelpDoc?id=customize_layoutoverview.htm&language=en
Hope this helps!
Happy coding!
Best regards,
Martijn Schwärzer